Cloning and expression of chicken 20-hydroxysteroid dehydrogenase
نویسندگان
چکیده
منابع مشابه
Cloning and expression of chicken 20-hydroxysteroid dehydrogenase.
The ligand specificity and activation of steroid receptors depend considerably on the enzymatic activities involved in local pre-receptor synthesis and the metabolism of the steroids. Several enzymes in particular, steroid dehydrogenases have been shown to participate in this process. Here we report the isolation of 20-hydroxysteroid dehydrogenase (ch20HSD) cDNA from chicken intestine and the d...
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17 beta-Hydroxysteroid dehydrogenase (17 beta-HSD) is an enzyme crucial to the regulation of intracellular levels of biologically active steroid hormones in a variety of tissues. Here, we report the isolation, structure, and characterization of a cDNA encoding the human 17 beta-HSD type 2. A 1.4-kilobase cDNA was identified, and DNA sequence analysis indicated that 17 beta-HSD type 2 was a prot...
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متن کاملChicken 11beta-hydroxysteroid dehydrogenase type 2: partial cloning and tissue distribution.
NAD(+)-dependent 11beta-hydroxysteroid dehydrogenase (11HSD2) converts glucocorticoids to 11-oxo derivatives and thus decreases their local concentration and prevents them from activating corticosteroid receptors. In this paper we report the partial cloning, characterization and tissue distribution of chicken 11HSD2. A cDNA of 991bp was cloned from kidney mRNA by reverse transcription and polym...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2006
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme.1.02025